Community planners recognize that conditions in their metropolitan areas have a powerful influence on what they can accomplish at the neighborhood level. This report highlights the 14 metros that were the focus for investment by the Annie E. Casey Foundation in the 2000s. These 14 represent the diversity across America’s large metropolitan areas. The report is organized into three sections. Section 1 introduces the 14 Casey metros using background indicators (e.g., on demographic conditions, social conditions and poverty levels). Section 2 examines the dynamics of the economies of these metropolitan areas since 2000, and Section 3 does the same for their housing markets.